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FDA proposes new system for approving customized drugs

WASHINGTON (AP) — Federal health officials on Monday laid out a proposal to spur development of customized treatments for patients with hard-to-treat diseases, including for rare genetic conditions that the pharmaceutical industry has long considered unprofitable. The preliminary Food and Drug Administration guidelines, if implemented, would create a new pathway for bespoke therapies that have only been tested in a handful of patients due to the challenges of conducting larger studies. The FDA announcement specifically mentions gene editing, although agency officials said the new ...

ICE officer training is ‘deficient’ and ‘broken,’ former agency lawyer tells congressional forum

WASHINGTON (AP) — A former U.S. Immigration and Customs Enforcement lawyer who was responsible for training new deportation officers warned Monday that the agency’s training program for new recruits is “deficient, defective and broken.” Ryan Schwank’s comments during a forum held by congressional Democrats come at a time of intense scrutiny of the officers tasked with carrying out President Donald Trump’s mass deportation agenda. Critics, including rights groups and Democratic politicians, have accused deportation officers of using excessive force when arresting immigrants, ...

Supreme Court agrees to hear from oil and gas companies trying to block climate change lawsuits

WASHINGTON (AP) — The Supreme Court said Monday that it will hear from oil and gas companies trying to block lawsuits seeking to hold the industry liable for billions of dollars in damage linked to climate change. The conservative-majority court agreed to take up a case from Boulder, Colorado, one of multiple lawsuits alleging the companies deceived the public about how fossil fuels contribute to climate change. Governments around the country have sought damages totaling billions of dollars, arguing it’s necessary to help pay for rebuilding after wildfires, rising sea levels and ...

Met Opera’s 2026-27 season has 17 productions, its fewest in at least 60 years

NEW YORK (AP) — Despite encouraging box office figures for the season’s first half, the financially strapped Metropolitan Opera scaled back its 2026-27 schedule with its fewest productions in at least 60 years. The Met announced Thursday it will present 17 productions, its lowest total in a non-truncated season since the company moved to Lincoln Center in 1966. There are just five new stagings, and revivals of three popular operas account for 71 of the 187 individual opera performances (38%): Puccini’s “Tosca” and “La Boheme,” and Verdi’s “Aida.” “It makes more ...

Horoscope

Stability nourishes. Dependability creates emotional ease. It’s why adventurers often spring off very secure anchors of solid relationships, habits and environs. Arguably, it’s those predictable elements that allow them to take bold risks of exploration through the uncertain and unknown. The steady Taurus lunar energy supports our bravest choices. ARIES (March 21-April 19). Experience has taught you exactly what you need and how to go about getting it. And though the order has been fulfilled, you still hunger for more. This keeps you curious and in motion. Rather than wrestling ...