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Obesity drugs show early promise against the hormonal disorder PMOS

(AP) — Charlotte Touzalin was still a young teenager when she began struggling with weight gain, abnormal periods and unwanted facial hair — the same puzzling symptoms that plagued her mom for decades and that no doctor could piece together. "I'd go home and I'd cry," said Touzalin, an 18-year-old college student from Colorado. "I didn't understand why all this weight was coming back or why my friends didn't have to shave their faces and I had to." Touzalin and her mom, Anne Schultz, were finally diagnosed with polyendocrine metabolic ovarian syndrome, a hormonal condition ...

Francis G. ‘Frank’ Koenig

With heavy hearts, we announce the passing of Francis G. "Frank" Koenig, who peacefully passed away at home on Aug. 1, 2026, with his loving wife, JoAnn, by his side. Born on Aug. 29, 1944, in Milwaukee, Wisconsin, Frank lived a life defined by faith, service, hard work and unwavering love ...

LeBron James picks his final NBA challenge, and Philadelphia was his ultimate answer

By TIM REYNOLDS AP Basketball Writer Those NBA schedule-makers who have been stuck in limbo can go ahead and hit overdrive now. LeBron James might have made their work pretty simple. Opening night, go ahead and expect Philadelphia at New York. Christmas Day, go ahead and expect Philadelphia on the schedule. National television games, go ahead and give Philadelphia a ton of those, too. The 76ers got perhaps the biggest bargain in sports history on Friday, when James — the NBA's all-time scoring king — announced he would be finishing his career in Philadelphia. Those NBA ...

Triolo, Mangum lift Pirates over Yankees 5-3

NEW YORK (AP) — Jared Triolo and Jake Mangum hit run-scoring singles against Fernando Cruz in the 10th inning, Jacob Gonzalez and Nick Gonzales homered off Gerrit Cole and the Pittsburgh Pirates beat the New York Yankees 5-3 Wednesday in the opener of a day-night doubleheader. Ben Rice tied the score with his 30th home run, a three-run drive in the seventh inning off Carmen Mlodzinski. Triolo and Mangum drove in runs off Cruz (4-4), who allowed two hits and two walks while getting just one out. Mason Montgomery (3-3) pitched 1 1/3 scoreless innings and Gregory Soto got three ...

Trump officials want to make testosterone drugs easier to prescribe. Is that a good idea?

WASHINGTON (AP) — Officials under President Donald Trump want to make it easier for men to get a prescription for testosterone, the latest shift in a decades-long debate over the benefits and risks of replacing the hormone that affects sex drive, mood and other health factors. The move, backed by Health Secretary Robert F. Kennedy Jr. and other top officials, aligns with the advice of many online influencers and podcasters, including men's health gurus who tout the hormone as a way to boost muscle and energy. On Tuesday, Defense Secretary Pete Hegseth said the military would begin ...

World Cup quarterfinals set

MIAMI GARDENS, Fla. (AP) — More World Cup teams. Same World Cup story. This edition started with 48 teams; it's now down to eight, with six of those from Europe. And unless Morocco pulls off a series of surprising outcomes over the final two weeks, the champion will come from Europe or South America. Again. As always. A tournament that has been around for nearly a century — the first World Cup was in 1930 — has been contested on 22 previous occasions. The champions: 12 from Europe, 10 from South America, zero from the rest of the globe combined. This year's quarterfinal ...